| Date | Transaction | |||
| 4/30/08 | Optioned INF Brian Buscher to Triple-A Rochester. | |||
| 4/25/08 | Activated OF Michael Cuddyer from the 15-day disabled list; Recalled RHP Bobby Korecky from Triple-A Rochester; Optioned LHP Francisco Liriano to Triple-A Rochester. | |||
| 4/24/08 | Optioned OF Denard Span to Triple-A Rochester. | |||
| 4/19/08 | Placed SS Adam Everett on the 15-day disabled list, retroactive to April 15, with a right shoulder strain and recalled INF Brian Buscher from Triple-A Rochester. | |||
| 4/12/08 | Recalled LHP Francisco Liriano from Triple-A Rochester. | |||
| 4/11/08 | Placed RHP Kevin Slowey on the 15-day disabled list, retroactive to April 4, with a right biceps strain. | |||
| 4/4/08 | Placed OF Michael Cuddyer on the 15-day disabled list with a dislocated right index finger; Recalled OF Denard Span from Triple-A Rochester. | |||